Ozempic (semaglutide) use continues to rise for both diabetes management and weight loss. A growing number of users are reporting concerning oral side effects, dubbed “Ozempic teeth.” This phenomenon refers to a range of dental issues that patients have linked to these types of medications, including tooth decay, sensitivity, enamel erosion, and even tooth loss.
Ozempic is a GLP-1 (glucagon-like peptide-1) receptor agonist that mimics the action of the GLP-1 hormone which helps regulate blood sugar levels and appetite. They are a class of medications commonly prescribed to manage type 2 diabetes and support weight loss in individuals with obesity. Popular options include:
Ozempic® (semaglutide)
Wegovy® (semaglutide)
Mounjaro® / Zepbound™ (tirzepatide)
Saxenda® / Victoza® (liraglutide)
Trulicity® (dulaglutide)
Byetta® / Bydureon® (exenatide)
Dr Takashima MD and Ahmed MD cite several mouth related affects of taking ozempic type medications including:
Reduced saliva production is one of the most commonly reported side effects. Saliva plays a critical role in neutralizing acids, washing away food particles, and protecting tooth enamel. When it decreases, the risk of cavities and gum disease increases significantly.
According to FDA data, up to 20% of patients on Ozempic experience nausea, with 5–9% reporting vomiting. Stomach acid exposure during vomiting can erode enamel and lead to heightened tooth sensitivity and damage.
Appetite suppression from GLP-1 medications can result in inadequate nutrient intake, particularly of vitamins essential for oral health—such as vitamin C, vitamin D, and B-complex vitamins. These deficiencies can weaken gums and impair tissue healing.
Some patients report reduced motivation to maintain proper oral hygiene due to feelings of nausea or fatigue, further increasing the risk of plaque buildup, gingivitis, and tooth decay.
Drink plenty of water throughout the day to combat dry mouth and promote natural saliva production.
Consider using milk based products like Tooth Mousee to help relieve dry mouth or chewing sugar-free gum to encourage salivation.
Avoid overly restrictive eating patterns. Ensure you’re consuming adequate calcium, vitamin D, and other nutrients vital for strong teeth and healthy gums.
Brush twice daily with fluoride toothpaste, floss after brushing or interdental brushes (Pixters) with toothpaste between teeth, and consider using a soft-bristled toothbrush if your gums are sensitive.
Limit or avoid alcohol, caffeine, and tobacco, which can exacerbate dry mouth.
If you're using a Ozempic style medication, and notice any of the following signs, it’s important to consult your dentist or healthcare provider promptly:
New or worsening tooth sensitivity
Bleeding or swollen gums
Persistent bad breath
Loose or broken teeth
Frequent nausea or vomiting
Early intervention can prevent irreversible damage and help preserve both your oral and general health.
References
U.S. Food and Drug Administration (FDA). (2023). Ozempic (semaglutide): Side Effect Profile.
Otolaryngologic Side Effects of GLP-1 Receptor Agonists. The Laryngoscope . DOI: 10.1002/lary.30567
Australian Dental Association (ADA). Dry Mouth (Xerostomia). Retrieved from ada.org.au
542 Main South Road Old Noarlunga SA 5168
Call us: 08 83272737 Text us: 0466 033 499
Monday - Thursday: 8:00 am – 5:00 pm
Friday: 8:00 am - 3:00 pm
Saturday / Sunday : Closed